DESCRIPTION

Sertraline HCl is a selective serotonin reuptake inhibitor (SSRI) for oral administration. It is chemically unrelated to other SSRIs, tricyclic, tetracyclic, or other available antidepressant agents. It has a molecular weight of 342.7. Sertraline hydrochloride has the following chemical name: (1S-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-nanphthalenamine hydrochloride. The empirical formula is C17H17NCl2·HCl.

Sertraline hydrochloride is a white crystalline powder that is slightly soluble in water and isopropyl alcohol, and sparingly soluble in ethanol.

Zoloft is supplied for oral administration as scored tablets containing sertraline hydrochloride equivalent to 25, 50 and 100 mg and the following inactive ingredients: dibasic calcium phosphate dihydrate, Dy & C Yellow #10 aluminum lake (in 25 mg tablet), FD & C Blue #1 aluminum lake (in 25 mg tablet), FD & C Red #40 aluminum lake (in 25 mg tablet), FD&C Blue #2 aluminum lake (in 50 mg tablet), hydroxypropyl cellulose, hydroxypropyl methylcellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, sodium starch glycolate, synthetic yellow iron oxide (in 100 mg tablet), and titanium dioxide.

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Zoloft
Active Ingredients: Sertraline
Representative Names: Zoloft
Available Product Images:

What are sertraline tablets?
What should my health care professional know before I take sertraline?
How should I take this medicine?
What if I miss a dose?
What drug(s) may interact with sertraline?
What side effects may I notice from taking sertraline?
What should I watch for while taking sertraline?
Where can I keep my medicine?

What are sertraline tablets? (Back to top)
SERTRALINE (Zoloft®) is an antidepressant. It helps to improve a depressed person's mood. Sertraline can also help people with an obsessive compulsive disorder, panic attacks, post-trauma stress, or social anxiety. Sertraline may also be prescribed for other purposes, like premenstrual dysphoric disorder (PMDD), a severe type of premenstrual syndrome. Generic sertraline tablets are not yet available.

What should my health care professional know before I take sertraline? (Back to top)
They need to know if you have any of these conditions:
• diabetes
• heart disease
• liver disease
• receiving electroconvulsive therapy
• seizures (convulsions)
• suicidal thoughts
• an unusual or allergic reaction to sertraline, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I take this medicine? (Back to top)
Take sertraline tablets by mouth. Follow the directions on the prescription label. Swallow the tablets with a drink of water. You may take sertraline with or without food. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your prescriber's advice.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose? (Back to top)
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take double or extra doses.

What drug(s) may interact with sertraline? (Back to top)
Sertraline has the potential to interact with a variety of medications, check with your healthcare professional. The following list contains some of these interactions.

Zoloft
sertraline (SER tra leen)

What is the most important information I should know about Zoloft?
• Do not stop taking Zoloft without first talking to your doctor. It may take 4 weeks or more for you to start feeling better and you may experience unpleasant side effects if you stop taking Zoloft suddenly.

What is Zoloft?
• Zoloft is in a class of drugs called selective serotonin reuptake inhibitors. Zoloft affects chemicals in the brain that may become unbalanced and cause depression, panic or anxiety, obsessive or compulsive symptoms, or other psychiatric symptoms.
• Zoloft is used to treat depression, obsessive-compulsive disorder, panic disorder, posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), and social anxiety disorder, also known as social phobia.
• Zoloft may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking Zoloft?
• Do not take Zoloft if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) during the last 2 weeks. Serious, and sometimes fatal, reactions have occurred when these medicines have been used together.
• Do not take Zoloft if you are taking pimozide (Orap). A dangerous drug interaction could result.
• Before taking Zoloft, tell your doctor if you
· have liver disease;
· have kidney disease;
· suffer from seizures; or
· suffer from mania or have suicidal thoughts.
• You may not be able to take Zoloft, or you may need a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
• Zoloft is in the FDA pregnancy category C. This means that it is unknown whether it will be harmful to an unborn baby. Do not take Zoloft without first talking to your doctor if you are pregnant or could become pregnant during treatment.
• It is not known whether Zoloft passes into breast milk. Do not take Zoloft without first talking to your doctor if you are breast-feeding a baby.

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